Did you know that FIGO TINTO® contains compounds that could prevent or reverse fat accumulation in the liver? A recent study confirms this using advanced separation techniques.
Researchers conducted a bioguided search for anti-steatotic compounds present in Opuntia stricta var. dillenii (TINTO FIG®), identifying fractions capable of reducing fat accumulation in liver cells. The results offer a new natural approach to combating non-alcoholic fatty liver disease (NAFLD).
What was investigated?
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Extracts of HIGO TINTO® were obtained and fractionated by fast centrifugal partition chromatography (FCPC) .
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Each fraction was evaluated on human hepatocytes (HepG2 cell line) treated with oleic/palmitic acid to induce steatosis.
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They were measured:
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Accumulation of intracellular lipids (Oil Red O staining)
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Cell Viability
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Composition of active metabolites
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Key results
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Several fractions with significant antisteatotic activity were identified.
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The active fractions reduced fat accumulation without affecting cell viability.
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They contained compounds such as:
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Betalains
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Isorhamnetin and flavonoid derivatives
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Ferulic acid and minor phenolic compounds
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Why is it important?
Non-alcoholic fatty liver disease (NAFLD) is a growing condition, related to:
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High-fat diets
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Sedentary lifestyle
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Insulin resistance
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Hepatic oxidative stress
The compounds in FIGO TINTO® act as follows:
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Decreasing lipogenesis
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Stimulating β-oxidation
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Neutralizing hepatic free radicals
Current application
This profile makes it an ideal ingredient for:
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Supplements focused on liver health
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Antioxidant and metabolic formulas
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NAFLD or sluggish liver prevention supplements
Related products from Tuno Canarias
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Dried RED FIG® powder : rich in flavonoids, betalains and fiber that help balance liver metabolism
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HIGO TINTO® BOOST : functional energy to combat daily metabolic stress
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Digestive Creamer : with probiotics, Q10 and ginkgo biloba to support gut microbiota and detox
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HIGO TINTO® Family Max : functional antioxidant with no added sugar, for family use
Conclusion
This study provides novel evidence on the use of FIG TINTO® extracts as a functional agent to combat fat accumulation in the liver . Its anti-steatotic effect makes it an ideal candidate for overall liver health.
The liver also needs natural allies. The TINTO FIG® knows how to take care of it.
Reference
Bertrand, M., et al. (2024)
A bio-guided search of anti-steatotic compounds in Opuntia stricta var. dillenii by fast centrifugal partition chromatography
Food Chemistry: Molecular Sciences, Vol. 6, 100262.
DOI: 10.1016/j.fochms.2024.100262
